Affiliated Faculty
Down syndrome and related topics are central to the research programs of a growing number of neuroscience labs at Stanford. In concert with basic research, experienced clinicians at the Stanford Hospital & Clinics focus on care and support for Down syndrome individuals. Led by Drs. Garner, Heller, and Feldman, Co-Directors of the Down Syndrome Research Center, we are collaborating to help people with Down syndrome lead healthy and happy lives by rapidly and effectively applying research discoveries to useful treatments.
Please scroll down to learn about this talented group of scientists and doctors!
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Dr. Craig Garner, Co-Director, is studying how abnormal synaptic signaling underlies cognitive dysfunction in mouse models of Down syndrome, as well as drug therapies to address deficits in memory function. More » |
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In his lab, Dr. Craig Heller, Co-Director, studies memory and learning, sleep architecture and circadian rhythms in Down syndrome mice in the context of drug therapies. More » |
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Dr. Heidi Feldman, Co-Director, is a developmental-behavioral pediatrician studying language development in children with learning disabilities. More » |
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Dr. Katrin Andreasson’s group investigates the molecular and cellular mechanisms of Alzheimer’s disease, with special interest in Down syndrome due to trisomy of the Alzheimer’s disease-related APP gene. More » |
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Using genetic tools Dr. Ting-Ting Huang hopes to learn more about how genetic modifiers modulate the disease process in Down syndrome. More » |
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Dr. Dan Madison uses electrophysiological and molecular genetic approaches to understand the mechanisms underlying normal and abnormal brain function in mouse models of Down syndrome. More » |
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Using electrophysiological, anatomical and molecular techniques, Dr. Rob Malenka is characterizing the abnormalities in neuronal communication in various mouse models of Down syndrome. More » |
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Dr. Melanie Manning, Director of the Center for Down syndrome at Stanford's Lucile Packard Children's Hospital, is a pediatrician and clinical geneticist with a focus on children and adults with chromosome abnormalities. More » |
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To examine how genetic factors, brain structure and function, and environmental factors impact the development and progress of individuals with Down syndrome, Dr. Alan Reiss uses advanced research tools such as neuroimaging, genetic analyses and neurobehavioral assessments. More » |
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Dr. Richard Tsien employs various research methods such as electrophysiology, imaging, and cDNA arrays to explore the idea that abnormal synaptic signaling between neurons may cause cognitive dysfunction in Down syndrome. More » |
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Dr. Tony Wyss-Coray is taking advantage of mouse models to find ways in which the brain's own immune mechanisms can be used to protect against Alzheimer's disease related neurodegeneration in Down syndrome. More » |
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With the help of mouse models, Dr. Yanmin Yang's laboratory is defining molecular and cellular mechanisms important for maintaining and sustaining neurons that may degenerate in Down syndrome. More » |
